Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

IMPORTANCE: Early exposure to complex dietary proteins may increase the risk of type 1 diabetes in children with genetic disease susceptibility. There are no intact proteins in extensively hydrolyzed formulas. OBJECTIVE: To test the hypothesis that weaning to an extensively hydrolyzed formula decrea...

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Bibliografske podrobnosti
izdano v:JAMA
Main Authors: Knip, Mikael, Åkerblom, Hans K., Al Taji, Eva, Becker, Dorothy, Bruining, Jan, Castano, Luis, Danne, Thomas, de Beaufort, Carine, Dosch, Hans-Michael, Dupre, John, Fraser, William D., Howard, Neville, Ilonen, Jorma, Konrad, Daniel, Kordonouri, Olga, Krischer, Jeffrey P., Lawson, Margaret L., Ludvigsson, Johnny, Madacsy, Laszlo, Mahon, Jeffrey L., Ormisson, Anne, Palmer, Jerry P., Pozzilli, Paolo, Savilahti, Erkki, Serrano-Rios, Manuel, Songini, Marco, Taback, Shayne, Vaarala, Outi, White, Neil H., Virtanen, Suvi M., Wasikowa, Renata
Format: Artigo
Jezik:Inglês
Izdano: American Medical Association 2018
Teme:
Original Investigation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833549/
https://ncbi.nlm.nih.gov/pubmed/29297078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2017.19826
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