Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

IMPORTANCE: Early exposure to complex dietary proteins may increase the risk of type 1 diabetes in children with genetic disease susceptibility. There are no intact proteins in extensively hydrolyzed formulas. OBJECTIVE: To test the hypothesis that weaning to an extensively hydrolyzed formula decrea...

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Détails bibliographiques
Publié dans:JAMA
Auteurs principaux: Knip, Mikael, Åkerblom, Hans K., Al Taji, Eva, Becker, Dorothy, Bruining, Jan, Castano, Luis, Danne, Thomas, de Beaufort, Carine, Dosch, Hans-Michael, Dupre, John, Fraser, William D., Howard, Neville, Ilonen, Jorma, Konrad, Daniel, Kordonouri, Olga, Krischer, Jeffrey P., Lawson, Margaret L., Ludvigsson, Johnny, Madacsy, Laszlo, Mahon, Jeffrey L., Ormisson, Anne, Palmer, Jerry P., Pozzilli, Paolo, Savilahti, Erkki, Serrano-Rios, Manuel, Songini, Marco, Taback, Shayne, Vaarala, Outi, White, Neil H., Virtanen, Suvi M., Wasikowa, Renata
Format: Artigo
Langue:Inglês
Publié: American Medical Association 2018
Sujets:
Original Investigation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833549/
https://ncbi.nlm.nih.gov/pubmed/29297078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2017.19826
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