Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

IMPORTANCE: Early exposure to complex dietary proteins may increase the risk of type 1 diabetes in children with genetic disease susceptibility. There are no intact proteins in extensively hydrolyzed formulas. OBJECTIVE: To test the hypothesis that weaning to an extensively hydrolyzed formula decrea...

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Detalles Bibliográficos
Publicado en:JAMA
Main Authors: Knip, Mikael, Åkerblom, Hans K., Al Taji, Eva, Becker, Dorothy, Bruining, Jan, Castano, Luis, Danne, Thomas, de Beaufort, Carine, Dosch, Hans-Michael, Dupre, John, Fraser, William D., Howard, Neville, Ilonen, Jorma, Konrad, Daniel, Kordonouri, Olga, Krischer, Jeffrey P., Lawson, Margaret L., Ludvigsson, Johnny, Madacsy, Laszlo, Mahon, Jeffrey L., Ormisson, Anne, Palmer, Jerry P., Pozzilli, Paolo, Savilahti, Erkki, Serrano-Rios, Manuel, Songini, Marco, Taback, Shayne, Vaarala, Outi, White, Neil H., Virtanen, Suvi M., Wasikowa, Renata
Formato: Artigo
Idioma:Inglês
Publicado: American Medical Association 2018
Assuntos:
Original Investigation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833549/
https://ncbi.nlm.nih.gov/pubmed/29297078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2017.19826
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