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Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer
Sterol regulatory element-binding proteins (SREBPs) belong to a family of transcription factors that regulate the expression of genes required for the synthesis of fatty acids and cholesterol. Three SREBP isoforms, SREBP1a, SREBP1c, and SREBP2, have been identified in mammalian cells. SREBP1a and SR...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833501/ https://ncbi.nlm.nih.gov/pubmed/29449559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0330-6 |
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