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Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration

Fatty acid synthase (FASN), a lipogenic enzyme, is upregulated in colorectal cancer (CRC). Increased de novo lipid synthesis is thought to be a metabolic adaptation of cancer cells that promotes survival and metastasis; however, the mechanisms for this phenomenon are not fully understood. We show th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Zaytseva, Yekaterina Y., Harris, Jennifer W., Mitov, Mihail I., Kim, Ji Tae, Butterfield, D. Allan, Lee, Eun Y., Weiss, Heidi L., Gao, Tianyan, Evers, B. Mark
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662462/
https://ncbi.nlm.nih.gov/pubmed/25970773
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