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Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes

Glaucoma is characterized by a progressive loss of retinal ganglion cells and their axons, but the underlying biological basis for the accompanying neurodegeneration is not known. Accumulating evidence indicates that structural and functional abnormalities of astrocytes within the optic nerve head (...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Shim, Myoung Sup, Kim, Keun-Young, Bu, Jung Hyun, Nam, Hye Seung, Jeong, Seung Won, Park, Tae Lim, Ellisman, Mark H., Weinreb, Robert N., Ju, Won-Kyu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833440/
https://ncbi.nlm.nih.gov/pubmed/29459737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0171-8
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