KRAS induces lung tumorigenesis through microRNAs modulation

Oncogenic KRAS induces tumor onset and development by modulating gene expression via different molecular mechanisms. MicroRNAs (miRNAs) are small non-coding RNAs that have been established as main players in tumorigenesis. By overexpressing wild type or mutant KRAS (KRAS(G12D)) and using inducible h...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Shi, Lei, Middleton, Justin, Jeon, Young-Jun, Magee, Peter, Veneziano, Dario, Laganà, Alessandro, Leong, Hui-Sun, Sahoo, Sudhakar, Fassan, Matteo, Booton, Richard, Shah, Rajesh, Crosbie, Philip A. J., Garofalo, Michela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833396/
https://ncbi.nlm.nih.gov/pubmed/29440633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0243-9
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