EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy

The epidermal growth factor receptor (EGFR) pathway and Hippo signaling play an important role in the carcinogenesis of hepatocellular carcinoma (HCC). However, the crosstalk between these two pathways and its implications in targeted therapy remains unclear. We found that the activated EGFR signali...

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書誌詳細
出版年:Cell Death Dis
主要な著者: Xia, Hongwei, Dai, Xinyu, Yu, Huangfei, Zhou, Sheng, Fan, Zhenghai, Wei, Guoqing, Tang, Qiulin, Gong, Qiyong, Bi, Feng
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833379/
https://ncbi.nlm.nih.gov/pubmed/29449645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0302-x
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