Glycolysis promotes caspase-3 activation in lipid rafts in T cells

Resting T cells undergo a rapid metabolic shift to glycolysis upon activation in the presence of interleukin (IL)-2, in contrast to oxidative mitochondrial respiration with IL-15. Paralleling these different metabolic states are striking differences in susceptibility to restimulation-induced cell de...

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Publicat a:Cell Death Dis
Autors principals: Secinaro, Michael A., Fortner, Karen A., Dienz, Oliver, Logan, Angela, Murphy, Michael P., Anathy, Vikas, Boyson, Jonathan E., Budd, Ralph C.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833351/
https://ncbi.nlm.nih.gov/pubmed/29352186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0099-z
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