Proliferating γδ T cells manifest high and spatially confined caspase-3 activity

Caspase-8 serves two paradoxical roles in T lymphocytes: it initiates apoptosis following death receptor engagement, and is also indispensible for proliferation following T-cell antigen receptor (TCR) signalling. These opposing processes appear to be controlled by both spatial and quantitative diffe...

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Detalhes bibliográficos
Main Authors: Koenig, Andreas, Fortner, Karen A, King, Benjamin R, Madden, Jonathan, Buskiewicz, Iwona A, Budd, Ralph C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372744/
https://ncbi.nlm.nih.gov/pubmed/22117649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03540.x
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