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Histone methylation regulates Hif‐1 signaling cascade in activation of hepatic stellate cells

Liver fibrosis is characterized by deposition of excessive extracellular matrix (ECM). The major source of ECM is activated hepatic stellate cells (HSCs). Previously, we reported that hypoxia‐inducible factor‐1 (Hif‐1) regulates activation of HSCs through autophagy. In current work, human HSC cell l...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Hong, Fei, Wan, Lu, Liu, Jie, Huang, Ke, Xiao, Zhenmeng, Zhang, Yingjing, Shi, Chunwei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832973/
https://ncbi.nlm.nih.gov/pubmed/29511617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12379
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