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An allosteric link connecting the lipid-protein interface to the gating of the nicotinic acetylcholine receptor
The mechanisms underlying lipid-sensing by membrane proteins is of considerable biological importance. A unifying mechanistic question is how a change in structure at the lipid-protein interface is translated through the transmembrane domain to influence structures critical to protein function. Gati...
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| Publicado no: | Sci Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5832824/ https://ncbi.nlm.nih.gov/pubmed/29497086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22150-x |
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