De novo adipocyte differentiation from Pdgfrβ(+) preadipocytes protects against pathologic visceral adipose expansion in obesity

Pathologic expansion of white adipose tissue (WAT) in obesity is characterized by adipocyte hypertrophy, inflammation, and fibrosis; however, factors triggering this maladaptive remodeling are largely unknown. Here, we test the hypothesis that the potential to recruit new adipocytes from Pdgfrβ(+) p...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Shao, Mengle, Vishvanath, Lavanya, Busbuso, Napoleon C., Hepler, Chelsea, Shan, Bo, Sharma, Ankit X., Chen, Shiuhwei, Yu, Xinxin, An, Yu A., Zhu, Yi, Holland, William L., Gupta, Rana K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832777/
https://ncbi.nlm.nih.gov/pubmed/29497032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03196-x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky