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Adenovirus-Mediated Delivery of Decoy Hyper Binding Sites Targeting Oncogenic HMGA1 Reduces Pancreatic and Liver Cancer Cell Viability

High mobility group AT-hook 1 (HMGA1) protein is an oncogenic architectural transcription factor that plays an essential role in early development, but it is also implicated in many human cancers. Elevated levels of HMGA1 in cancer cells cause misregulation of gene expression and are associated with...

詳細記述

保存先:
書誌詳細
出版年:Mol Ther Oncolytics
主要な著者: Hassan, Faizule, Ni, Shuisong, Arnett, Tyler C., McKell, Melanie C., Kennedy, Michael A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Gene & Cell Therapy 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832671/
https://ncbi.nlm.nih.gov/pubmed/29511732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2018.01.002
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