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Adenovirus-Mediated Delivery of Decoy Hyper Binding Sites Targeting Oncogenic HMGA1 Reduces Pancreatic and Liver Cancer Cell Viability
High mobility group AT-hook 1 (HMGA1) protein is an oncogenic architectural transcription factor that plays an essential role in early development, but it is also implicated in many human cancers. Elevated levels of HMGA1 in cancer cells cause misregulation of gene expression and are associated with...
Gardado en:
| Publicado en: | Mol Ther Oncolytics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Gene & Cell Therapy
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5832671/ https://ncbi.nlm.nih.gov/pubmed/29511732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2018.01.002 |
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