Genetic and Small Molecule Inhibition of Arylamine N-acetyltransferase 1 Reduces Anchorage-Independent Growth in Human Breast Cancer Cell Line MDA-MB-231

Arylamine N-acetyltransferase 1 (NAT1) expression is reported to affect proliferation, invasiveness, and growth of cancer cells. MDA-MB-231 breast cancer cells were engineered such that NAT1 expression was elevated or suppressed, or treated with a small molecule inhibitor of NAT1. The MDA-MB-231 hum...

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Publicado en:Mol Carcinog
Main Authors: Stepp, Marcus W., Doll, Mark A., Carlisle, Samantha M., States, J. Christopher, Hein, David W.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832614/
https://ncbi.nlm.nih.gov/pubmed/29315819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22779
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