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Knockout of Human Arylamine N-Acetyltransferase 1 (NAT1) in MDA-MB-231 Breast Cancer Cells Leads to Increased Reserve Capacity, Maximum Mitochondrial Capacity, and Glycolytic Reserve Capacity
INTRODUCTION: Human arylamine N-acetyltransferase 1 (NAT1) is a phase II xenobiotic metabolizing enzyme found in almost all tissues. NAT1 can also hydrolyze acetyl-coenzyme A (acetyl-CoA) in the absence of an arylamine substrate. Expression of NAT1 varies between individuals and is elevated in sever...
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| 發表在: | Mol Carcinog |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6353662/ https://ncbi.nlm.nih.gov/pubmed/29964355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22869 |
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