Molecular Basis for DPY-30 Association to COMPASS-like and NURF Complexes

DPY-30 is a subunit of mammalian COMPASS-like complexes (complex of proteins associated with Set1) and regulates global histone H3 Lys-4 trimethylation. Here we report structural evidence showing that the incorporation of DPY-30 into COMPASS-like complexes is mediated by several hydrophobic interact...

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Published in:Structure
Main Authors: Tremblay, Véronique, Zhang, Pamela, Chaturvedi, Chandra-Prakash, Thornton, Janet, Brunzelle, Joseph S., Skiniotis, Georgios, Shilatifard, Ali, Brand, Marjorie, Couture, Jean-François
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832440/
https://ncbi.nlm.nih.gov/pubmed/25456412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.10.002
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