Structure and conformational dynamics of a COMPASS histone H3K4 methyltransferase complex

The methylation of histone 3 Lysine 4 (H3K4) is carried out by an evolutionarily conserved family of methyltransferases referred to as COMplex of Proteins ASsociated with Set1 (COMPASS). The activity of the catalytic SET domain (Su(var)3–9, Enhancer-of-zeste and Trithorax) is endowed through forming...

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Publicat a:Cell
Autors principals: Qu, Qianhui, Takahashi, Yohhei, Yang, Yidai, Hu, Hongli, Zhang, Yan, Brunzelle, Joseph S., Couture, Jean-Francois, Shilatifard, Ali, Skiniotis, Georgios
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108936/
https://ncbi.nlm.nih.gov/pubmed/30100186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.07.020
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