Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy

Exciting progress in the field of cancer immunotherapy has renewed the urgency of the need for basic studies of immunoregulation in both adaptive cell lineages and innate cell lineages. Here we found a central role for major histocompatibility complex (MHC) class I in controlling the phagocytic func...

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Publicado no:Nat Immunol
Main Authors: Barkal, Amira A., Weiskopf, Kipp, Kao, Kevin S., Gordon, Sydney R., Rosental, Benyamin, Yiu, Ying Y., George, Benson M., Markovic, Maxim, Ring, Nan G., Tsai, Jonathan M., McKenna, Kelly M., Ho, Po Yi, Cheng, Robin Z., Chen, James Y., Barkal, Layla J., Ring, Aaron M., Weissman, Irving L., Maute, Roy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832354/
https://ncbi.nlm.nih.gov/pubmed/29180808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-017-0004-z
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