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Immature Dendritic Cell Therapy Confers Durable Immune Modulation in an Antigen-Dependent and Antigen-Independent Manner in Nonobese Diabetic Mice

Dendritic cell (DC) immunotherapy has been effective for prevention of type 1 diabetes (T1D) in NOD mice but fails to protect if initiated after active autoimmunity. As autoreactivity expands inter- and intramolecularly during disease progression, we investigated whether DCs unpulsed or pulsed with...

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Détails bibliographiques
Publié dans:J Immunol Res
Auteurs principaux: Lo, Jeannette, Xia, Chang-Qing, Peng, Ruihua, Clare-Salzler, Michael J.
Format: Artigo
Langue:Inglês
Publié: Hindawi 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832131/
https://ncbi.nlm.nih.gov/pubmed/29651443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/5463879
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