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Characterization of Bone Marrow-Derived Dendritic Cells Developed in Serum-Free Media and their Ability to Prevent Type 1 Diabetes in Nonobese Diabetic Mice

Dendritic cells (DC) have been investigated as a cell-based therapy for Type 1 Diabetes (T1D). BM-DC expanded ex vivo with GM-CSF and IL-4 is typically cultured with fetal bovine serum (FBS). The effect of FBS on NOD BM-DC has not been extensively studied. In the present study we compare BM-DC gener...

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Publicat a:J Blood Disord Transfus
Autors principals: Looney, Ben M, Chernatynskaya, Anna V, Clare-Salzler, Michael J, Xia, Chang-Qing
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712959/
https://ncbi.nlm.nih.gov/pubmed/26779386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9864.1000206
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