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Transplantation of Hypoxic-Preconditioned Bone Mesenchymal Stem Cells Retards Intervertebral Disc Degeneration via Enhancing Implanted Cell Survival and Migration in Rats

OBJECTIVE: Special hypoxic and hypertonic microenvironment in intervertebral discs (IVDs) decreases the treatment effect of cell transplantation. We investigated the hypothesis that hypoxic preconditioning (HP) could improve the therapeutic effect of bone mesenchymal stem cells (BMSCs) to IVD degene...

詳細記述

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書誌詳細
出版年:Stem Cells Int
主要な著者: Wang, Weiheng, Wang, Yang, Deng, Guoying, Ma, Jun, Huang, Xiaodong, Yu, Jiangming, Xi, Yanhai, Ye, Xiaojian
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832130/
https://ncbi.nlm.nih.gov/pubmed/29535780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7564159
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