CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival

Despite multidisciplinary local and systemic therapeutic approaches, the prognosis for most patients with brain metastases is still dismal. The role of adaptive and innate anti-tumor response including the Human Leukocyte Antigen (HLA) machinery of antigen presentation is still unclear. We present d...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol Commun
Autori principali: Zeiner, P. S., Zinke, J., Kowalewski, D. J., Bernatz, S., Tichy, J., Ronellenfitsch, M. W., Thorsen, F., Berger, A., Forster, M. T., Muller, A., Steinbach, J. P., Beschorner, R., Wischhusen, J., Kvasnicka, H. M., Plate, K. H., Stefanović, S., Weide, B., Mittelbronn, M., Harter, P. N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831742/
https://ncbi.nlm.nih.gov/pubmed/29490700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0521-5
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