Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases

The activation of immune cells by targeting checkpoint inhibitors showed promising results with increased patient survival in distinct primary cancers. Since only limited data exist for human brain metastases, we aimed at characterizing tumor infiltrating lymphocytes (TILs) and expression of immune...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Harter, Patrick N., Bernatz, Simon, Scholz, Alexander, Zeiner, Pia S., Zinke, Jenny, Kiyose, Makoto, Blasel, Stella, Beschorner, Rudi, Senft, Christian, Bender, Benjamin, Ronellenfitsch, Michael W., Wikman, Harriet, Glatzel, Markus, Meinhardt, Matthias, Juratli, Tareq A., Steinbach, Joachim P., Plate, Karl H., Wischhusen, Jörg, Weide, Benjamin, Mittelbronn, Michel
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747372/
https://ncbi.nlm.nih.gov/pubmed/26517811
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