Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases

The activation of immune cells by targeting checkpoint inhibitors showed promising results with increased patient survival in distinct primary cancers. Since only limited data exist for human brain metastases, we aimed at characterizing tumor infiltrating lymphocytes (TILs) and expression of immune...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Harter, Patrick N., Bernatz, Simon, Scholz, Alexander, Zeiner, Pia S., Zinke, Jenny, Kiyose, Makoto, Blasel, Stella, Beschorner, Rudi, Senft, Christian, Bender, Benjamin, Ronellenfitsch, Michael W., Wikman, Harriet, Glatzel, Markus, Meinhardt, Matthias, Juratli, Tareq A., Steinbach, Joachim P., Plate, Karl H., Wischhusen, Jörg, Weide, Benjamin, Mittelbronn, Michel
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747372/
https://ncbi.nlm.nih.gov/pubmed/26517811
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