Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases

The activation of immune cells by targeting checkpoint inhibitors showed promising results with increased patient survival in distinct primary cancers. Since only limited data exist for human brain metastases, we aimed at characterizing tumor infiltrating lymphocytes (TILs) and expression of immune...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Harter, Patrick N., Bernatz, Simon, Scholz, Alexander, Zeiner, Pia S., Zinke, Jenny, Kiyose, Makoto, Blasel, Stella, Beschorner, Rudi, Senft, Christian, Bender, Benjamin, Ronellenfitsch, Michael W., Wikman, Harriet, Glatzel, Markus, Meinhardt, Matthias, Juratli, Tareq A., Steinbach, Joachim P., Plate, Karl H., Wischhusen, Jörg, Weide, Benjamin, Mittelbronn, Michel
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747372/
https://ncbi.nlm.nih.gov/pubmed/26517811
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