MIF Receptor CD74 is Restricted to Microglia/Macrophages, Associated with a M1‐Polarized Immune Milieu and Prolonged Patient Survival in Gliomas

The macrophage migration inhibitory factor (MIF) receptor CD74 is overexpressed in various neoplasms, mainly in hematologic tumors, and currently investigated in clinical studies. CD74 is quickly internalized and recycles after antibody binding, therefore it constitutes an attractive target for anti...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Zeiner, Pia S., Preusse, Corinna, Blank, Anna‐Eva, Zachskorn, Cornelia, Baumgarten, Peter, Caspary, Lixi, Braczynski, Anne K., Weissenberger, Jakob, Bratzke, Hansjürgen, Reiß, Sandy, Pennartz, Sandra, Winkelmann, Ria, Senft, Christian, Plate, Karl H., Wischhusen, Jörg, Stenzel, Werner, Harter, Patrick N., Mittelbronn, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029437/
https://ncbi.nlm.nih.gov/pubmed/25175718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12194
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