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How carrier size and valency modulate receptor-mediated signaling: understanding the link between binding and endocytosis of ICAM-1-targeted carriers
Targeting of drug carriers to endocytic cell-receptors facilitates intracellular drug delivery. Carrier size and number of targeting moieties (valency) influence cell binding and uptake. However, how these parameters influence receptor-mediated cell-signaling (the link between binding and uptake) re...
Shranjeno v:
| izdano v: | Biomacromolecules |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5831250/ https://ncbi.nlm.nih.gov/pubmed/27585187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.6b00493 |
| Oznake: |
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