In Vitro Modeling of Human Germ Cell Development Using Pluripotent Stem Cells

Due to differences across species, the mechanisms of cell fate decisions determined in mice cannot be readily extrapolated to humans. In this study, we developed a feeder- and xeno-free culture protocol that efficiently induced human pluripotent stem cells (iPSCs) into PLZF+/GPR125+/CD90+ spermatogo...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Zhao, Yuncheng, Ye, Shicheng, Liang, Dongli, Wang, Pengxiang, Fu, Jing, Ma, Qing, Kong, Ruijiao, Shi, Linghong, Gong, Xueping, Chen, Wei, Ding, Wubin, Yang, Wenjing, Zhu, Zijue, Chen, Huixing, Sun, Xiaoxi, Zhu, Jun, Li, Zheng, Wang, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830957/
https://ncbi.nlm.nih.gov/pubmed/29398481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.001
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