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Epigenetic re-programming of the Germ Cell Nuclear Factor gene is required for proper differentiation of induced pluripotent cells

Somatic cells have been reprogrammed into induced pluripotent stem (iPS) cells that recapitulate the pluripotent nature of embryonic stem (ES) cells. Reduced pluripotency and variable differentiation capacities have hampered progress with this technology for applications in regeneration medicine. We...

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Xehetasun bibliografikoak
Egile Nagusiak: Wang, Hongran, Wang, Xiaohong, Xu, Xueping, Zwaka, Thomas P., Cooney, Austin J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731425/
https://ncbi.nlm.nih.gov/pubmed/23495137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1367
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