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Epigenetic re-programming of the Germ Cell Nuclear Factor gene is required for proper differentiation of induced pluripotent cells
Somatic cells have been reprogrammed into induced pluripotent stem (iPS) cells that recapitulate the pluripotent nature of embryonic stem (ES) cells. Reduced pluripotency and variable differentiation capacities have hampered progress with this technology for applications in regeneration medicine. We...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731425/ https://ncbi.nlm.nih.gov/pubmed/23495137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1367 |
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