In Vitro Modeling of Human Germ Cell Development Using Pluripotent Stem Cells

Due to differences across species, the mechanisms of cell fate decisions determined in mice cannot be readily extrapolated to humans. In this study, we developed a feeder- and xeno-free culture protocol that efficiently induced human pluripotent stem cells (iPSCs) into PLZF+/GPR125+/CD90+ spermatogo...

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Bibliografske podrobnosti
izdano v:Stem Cell Reports
Main Authors: Zhao, Yuncheng, Ye, Shicheng, Liang, Dongli, Wang, Pengxiang, Fu, Jing, Ma, Qing, Kong, Ruijiao, Shi, Linghong, Gong, Xueping, Chen, Wei, Ding, Wubin, Yang, Wenjing, Zhu, Zijue, Chen, Huixing, Sun, Xiaoxi, Zhu, Jun, Li, Zheng, Wang, Yuan
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830957/
https://ncbi.nlm.nih.gov/pubmed/29398481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.001
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