Compartmentalization of HP1 Proteins in Pluripotency Acquisition and Maintenance

The heterochromatin protein 1 (HP1) family is involved in various functions with maintenance of chromatin structure. During murine somatic cell reprogramming, we find that early depletion of HP1γ reduces the generation of induced pluripotent stem cells, while late depletion enhances the process, wit...

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Published in:Stem Cell Reports
Main Authors: Zaidan, Nur Zafirah, Walker, Kolin J., Brown, Jaime E., Schaffer, Leah V., Scalf, Mark, Shortreed, Michael R., Iyer, Gopal, Smith, Lloyd M., Sridharan, Rupa
Format: Artigo
Language:Inglês
Published: Elsevier 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830946/
https://ncbi.nlm.nih.gov/pubmed/29358085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.12.016
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