Defining Reprogramming Checkpoints from Single-Cell Analyses of Induced Pluripotency

Elucidating the mechanism of reprogramming is confounded by heterogeneity due to the low efficiency and differential kinetics of obtaining induced pluripotent stem cells (iPSCs) from somatic cells. Therefore, we increased the efficiency with a combination of epigenomic modifiers and signaling molecu...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Tran, Khoa A., Pietrzak, Stefan J., Zaidan, Nur Zafirah, Siahpirani, Alireza Fotuhi, McCalla, Sunnie Grace, Zhou, Amber S., Iyer, Gopal, Roy, Sushmita, Sridharan, Rupa
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555151/
https://ncbi.nlm.nih.gov/pubmed/31067459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.056
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