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Defining Reprogramming Checkpoints from Single-Cell Analyses of Induced Pluripotency
Elucidating the mechanism of reprogramming is confounded by heterogeneity due to the low efficiency and differential kinetics of obtaining induced pluripotent stem cells (iPSCs) from somatic cells. Therefore, we increased the efficiency with a combination of epigenomic modifiers and signaling molecu...
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| Udgivet i: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6555151/ https://ncbi.nlm.nih.gov/pubmed/31067459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.056 |
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