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Interdependence theory of tissue failure: bulk and boundary effects

The mortality rate of many complex multicellular organisms increases with age, which suggests that net ageing damage is accumulative, despite remodelling processes. But how exactly do these little mishaps in the cellular level accumulate and spread to become a systemic catastrophe? To address this q...

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Bibliografiske detaljer
Udgivet i:R Soc Open Sci
Main Authors: Suma, Daniel, Acun, Aylin, Zorlutuna, Pinar, Vural, Dervis Can
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society Publishing 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830746/
https://ncbi.nlm.nih.gov/pubmed/29515857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.171395
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