Toll-Like Receptor 9–Dependent AMPKα Activation Occurs via TAK1 and Contributes to RhoA/ROCK Signaling and Actin Polymerization in Vascular Smooth Muscle Cells

Traditionally, Toll-like receptor 9 (TLR9) signals through an MyD88-dependent cascade that results in proinflammatory gene transcription. Recently, it was reported that TLR9 also participates in a stress tolerance signaling cascade in nonimmune cells. In this noncanonical pathway, TLR9 binds to and...

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Detaylı Bibliyografya
Yayımlandı:J Pharmacol Exp Ther
Asıl Yazarlar: McCarthy, Cameron G., Wenceslau, Camilla F., Ogbi, Safia, Szasz, Theodora, Webb, R. Clinton
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2018
Konular:
Cardiovascular
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830639/
https://ncbi.nlm.nih.gov/pubmed/29348267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.245746
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