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LIPOXIN A(4) MEDIATES AORTIC CONTRACTION VIA RHOA/RHO KINASE, ENDOTHELIAL DYSFUNCTION AND REACTIVE OXYGEN SPECIES
BACKGROUND: Lipoxin A4 (LXA(4)) is a biologically active product generated from arachidonic acid by lipoxygenase action. The production of lipoxins is enhanced by aspirin through acetylation of cyclooxygenase-2, via a mechanism known as “aspirin-triggered lipoxin”. LXA(4) has both anti-inflammatory...
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| Publicado no: | J Vasc Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4323151/ https://ncbi.nlm.nih.gov/pubmed/25612650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000371490 |
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