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Chimeric peptide EP45 as a dual agonist at GLP-1 and NPY2R receptors
We report the design and target validation of chimeric peptide EP45, a novel 45 amino acid monomeric dual agonist peptide that contains amino acid sequence motifs present within the blood glucose-lowering agent exendin-4 (Ex-4) and the appetite-suppressing agent PYY(3–36). In a new high-throughput F...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5830615/ https://ncbi.nlm.nih.gov/pubmed/29491394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22106-1 |
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