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Diabetes Outfoxed by GLP-1?
Foxo1, a member of the Fox0 subfamily of winged-helix forkhead transcription factors, is a target of insulin and insulin-like growth factor–1 (IGF-1) signal transduction pathways that activate protein kinase B (PKB) in pancreatic β cells. Foxo1 is a substrate for PKB, and its phosphorylation results...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909599/ https://ncbi.nlm.nih.gov/pubmed/15671479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/stke.2682005pe2 |
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