An Interaction between Serotonin Receptor Signaling and Dopamine Enhances Goal-Directed Vigor and Persistence in Mice

The functionally selective 5-HT2C receptor ligand SB242084 can increase motivation and have rapid onset anti–depressant-like effects. We sought to identify the specific behavioral effects of SB242084 treatment and elucidate the mechanism in female and male mice. Using a quantitative behavioral appro...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Bailey, Matthew R., Goldman, Olivia, Bello, Estefanía P., Chohan, Muhammad O., Jeong, Nuri, Winiger, Vanessa, Chun, Eileen, Schipani, Elke, Kalmbach, Abigail, Cheer, Joseph F., Balsam, Peter D., Simpson, Eleanor H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830508/
https://ncbi.nlm.nih.gov/pubmed/29367407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2088-17.2018
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