PIK3CA mutation is associated with increased local failure in lung stereotactic body radiation therapy (SBRT)

OBJECTIVES: Hyperactivation of the phosphatidylinositol-3-kinase (PI3K) pathway has been associated with radioresistance. It is unclear whether such mutations confer suboptimal local control for patients who receive lung stereotactic body radiation therapy (SBRT). Our objective was to examine whethe...

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Bibliografske podrobnosti
izdano v:Clin Transl Radiat Oncol
Main Authors: Lockney, Natalie A., Yang, T. Jonathan, Barron, David, Gelb, Emily, Gelblum, Daphna Y., Yorke, Ellen, Shi, Weiji, Zhang, Zhigang, Rimner, Andreas, Wu, Abraham J.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830173/
https://ncbi.nlm.nih.gov/pubmed/29503876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctro.2017.11.002
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