PIK3CA mutation is associated with increased local failure in lung stereotactic body radiation therapy (SBRT)

OBJECTIVES: Hyperactivation of the phosphatidylinositol-3-kinase (PI3K) pathway has been associated with radioresistance. It is unclear whether such mutations confer suboptimal local control for patients who receive lung stereotactic body radiation therapy (SBRT). Our objective was to examine whethe...

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Publicado en:Clin Transl Radiat Oncol
Autores principales: Lockney, Natalie A., Yang, T. Jonathan, Barron, David, Gelb, Emily, Gelblum, Daphna Y., Yorke, Ellen, Shi, Weiji, Zhang, Zhigang, Rimner, Andreas, Wu, Abraham J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830173/
https://ncbi.nlm.nih.gov/pubmed/29503876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctro.2017.11.002
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