PIK3CA mutation is associated with increased local failure in lung stereotactic body radiation therapy (SBRT)

OBJECTIVES: Hyperactivation of the phosphatidylinositol-3-kinase (PI3K) pathway has been associated with radioresistance. It is unclear whether such mutations confer suboptimal local control for patients who receive lung stereotactic body radiation therapy (SBRT). Our objective was to examine whethe...

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Detalhes bibliográficos
Publicado no:Clin Transl Radiat Oncol
Main Authors: Lockney, Natalie A., Yang, T. Jonathan, Barron, David, Gelb, Emily, Gelblum, Daphna Y., Yorke, Ellen, Shi, Weiji, Zhang, Zhigang, Rimner, Andreas, Wu, Abraham J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830173/
https://ncbi.nlm.nih.gov/pubmed/29503876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctro.2017.11.002
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