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PIK3CA mutation is associated with increased local failure in lung stereotactic body radiation therapy (SBRT)

OBJECTIVES: Hyperactivation of the phosphatidylinositol-3-kinase (PI3K) pathway has been associated with radioresistance. It is unclear whether such mutations confer suboptimal local control for patients who receive lung stereotactic body radiation therapy (SBRT). Our objective was to examine whethe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Transl Radiat Oncol
Hauptverfasser: Lockney, Natalie A., Yang, T. Jonathan, Barron, David, Gelb, Emily, Gelblum, Daphna Y., Yorke, Ellen, Shi, Weiji, Zhang, Zhigang, Rimner, Andreas, Wu, Abraham J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830173/
https://ncbi.nlm.nih.gov/pubmed/29503876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctro.2017.11.002
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