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A Network of Genetic Effects on Non-Demented Cognitive Aging: Alzheimer’s Genetic Risk (CLU + CR1 + PICALM) Intensifies Cognitive Aging Genetic Risk (COMT + BDNF) Selectively for APOE ε4 Carriers
BACKGROUND: Trajectories of complex neurocognitive phenotypes in preclinical aging may be produced differentially through selective and interactive combinations of genetic risk. OBJECTIVE: We organize three possible combinations into a “network” of genetic risk indices derived from polymorphisms ass...
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| Publicado no: | J Alzheimers Dis |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5830167/ https://ncbi.nlm.nih.gov/pubmed/29480189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170909 |
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