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Genetic variations in the CLU and PICALM genes are associated with cognitive function in the oldest old

Recently, two large, and independent genome wide association studies of late-onset Alzheimer’s disease (AD) established association with the same rs11136000 variation in the clusterin (CLU) gene. In addition, one variation, rs3851179, in the phosphatidylinositol binding clathrin assembly protein (PI...

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Autori principali: Mengel-From, Jonas, Christensen, Kaare, McGue, Matt, Christiansen, Lene
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042035/
https://ncbi.nlm.nih.gov/pubmed/20739100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.07.016
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