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Synergistic associations of COMT and BDNF with executive function in aging are selective and modified by APOE

Genetic polymorphisms of Catechol-O-methyltransferase (COMT) and Brain-derived neurotrophic factor (BDNF) have shown promising but inconsistent linkages with executive function (EF) in normal aging. We tested (a) independent contributions of COMT and BDNF risk, (b) potential magnification by risk-re...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Sapkota, Shraddha, Vergote, David, Westaway, David, Jhamandas, Jack, Dixon, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268316/
https://ncbi.nlm.nih.gov/pubmed/25107496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.06.020
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