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Identification of large rearrangements in cancer genomes with barcode linked reads

Large genomic rearrangements involve inversions, deletions and other structural changes that span Megabase segments of the human genome. This category of genetic aberration is the cause of many hereditary genetic disorders and contributes to pathogenesis of diseases like cancer. We developed a new a...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Xia, Li C, Bell, John M, Wood-Bouwens, Christina, Chen, Jiamin J, Zhang, Nancy R, Ji, Hanlee P
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829571/
https://ncbi.nlm.nih.gov/pubmed/29186506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1193
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