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Identification of large rearrangements in cancer genomes with barcode linked reads

Large genomic rearrangements involve inversions, deletions and other structural changes that span Megabase segments of the human genome. This category of genetic aberration is the cause of many hereditary genetic disorders and contributes to pathogenesis of diseases like cancer. We developed a new a...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Xia, Li C, Bell, John M, Wood-Bouwens, Christina, Chen, Jiamin J, Zhang, Nancy R, Ji, Hanlee P
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829571/
https://ncbi.nlm.nih.gov/pubmed/29186506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1193
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