Linked read sequencing resolves complex genomic rearrangements in gastric cancer metastases

BACKGROUND: Genome rearrangements are critical oncogenic driver events in many malignancies. However, the identification and resolution of the structure of cancer genomic rearrangements remain challenging even with whole genome sequencing. METHODS: To identify oncogenic genomic rearrangements and re...

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Publicat a:Genome Med
Autors principals: Greer, Stephanie U., Nadauld, Lincoln D., Lau, Billy T., Chen, Jiamin, Wood-Bouwens, Christina, Ford, James M., Kuo, Calvin J., Ji, Hanlee P.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477353/
https://ncbi.nlm.nih.gov/pubmed/28629429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0447-8
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