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Import of TAT-Conjugated Propionyl Coenzyme A Carboxylase Using Models of Propionic Acidemia

Propionic acidemia is caused by a deficiency of the enzyme propionyl coenzyme A carboxylase (PCC) located in the mitochondrial matrix. Cell-penetrating peptides, including transactivator of transcription (TAT), offer a potential to deliver a cargo into the mitochondrion. Here, we investigated the de...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Collard, Renata, Majtan, Tomas, Park, Insun, Kraus, Jan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829486/
https://ncbi.nlm.nih.gov/pubmed/29378828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00491-17
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